Methods for Computational Gene Prediction

Author: William H. Majoros
Edition: 1
Binding: Paperback
ISBN: 0521706947
Publisher: Cambridge University Press

Methods for Computational Gene Prediction

Inferring the precise locations and splicing patterns of genes in DNA is a difficult but important task, with broad applications to biomedicine.
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The mathematical and statistical techniques that have been applied to this problem are surveyed and organized into a logical framework based on the theory of parsing. Both established approaches and methods at the forefront of current research are discussed. Numerous case studies of existing software systems are provided, in addition to detailed examples that work through the actual implementation of effective gene-predictors using hidden Markov models and other machine-learning techniques. Background material on probability theory, discrete mathematics, computer science, and molecular biology is provided,

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